What menopause really does to your brain, heart, gut, bones and skin – with Professor Mary Ryan

Age Better with Liz Earle

September 11, 2026 ∙ 48 mins
Episode 80

About

Hormones affect far more than fertility and menopause – they play a vital role in everything from heart and brain health to strong bones and a balanced gut. Professor of endocrinology Mary Ryan joins Liz to explain why looking after our hormones means taking greater control of our everyday health.


They discuss how declining oestrogen during perimenopause and menopause can impact our entire body as we age, and why midlife is a significant time to take stock.


Mary also shares ways to support our hormonal system through diet, exercise, sleep and stress management and talks about the importance of clearing oestrogen from the body.


In this episode:

·     Why the pituitary gland is hormone HQ

·     The importance of balancing blood sugar for our cortisol levels

·     How HRT can protect bone health

·     The link between declining oestrogen and high blood pressure

·     Why our hormonal system needs to be recharged like a phone

·     Eating more fibre to produce happy hormones

·     The risks associated with plastics and other endocrine disruptors

·     How healthy bowel movements help remove excess oestrogen from the body

·     Why vaginal oestrogen is an essential for women’s health


More from Mary:

·     Follow Mary on Instagram

·     Read Mary’s book, It’s Probably Your Hormones

·     Buy tickets for Mary’s women’s health conference, Empower Her


Get in touch with a question for Liz:

·     Email: podcast@lizearlewellbeing.com

·     WhatsApp: 07518 471 846


More from Liz:

·     How To Age

·     A Better Second Half

·     Follow Liz on Instagram

·     Follow Liz Earle Wellbeing on Instagram

 

Host: Liz Earle

Producer: Anouszka Tate (Fresh Air Production) 

Content Writer: Lucy Parley

Head of Brand: Ellie Smith


Some links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information.



 

Hosted on Acast. See acast.com/privacy for more information.

Information

Podcast

Age Better with Liz Earle

Episode

80

Date

September 11, 2026

Length

48 mins
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    What could reduce your risk of heart disease and stroke, lower inflammation, and make you less susceptible to depression? The answer, says nutritionist Emma Bardwell, is fibre. Emma’s back on the show by popular demand to explain why hitting 30 grams a day could transform everything from weight loss and mood to digestion and glowing […]

  • Should I be eating more salt or less?

    It’s one of the most confusing nutrition debates – should you be eating more salt or less? The answer might surprise you, because it depends on your lifestyle. If you’re cooking from scratch or you’re very active the advice is very different than if ultra-processed foods are part of your diet. Liz explains why salt […]

  • The 5 pillars to prevent dementia and stroke – with Dr Partha Nandi

    Dr Partha Nandi is a gastroenterologist who wants you to know that the key to preventing stroke, Alzheimer’s and Parkinson’s might not lie in the brain at all – it lies in the gut. He shares how inflammation in your gut today could be affecting your brain decades from now. And he reveals the five simple pillars […]

  • Caffeine vs adaptogens: how to feel more energised – with Schia Mitchell Sinclair

    Always running low on energy? Herbal polypharmacist Schia Mitchell Sinclair says it might be time to kick the caffeine habit, and explore adaptogens instead. This episode is brought to you by The Herbtender. If after hearing this conversation you want to try their supplements and herbal teas for yourself, you can use code LIZLOVES for 20% […]

  • Pilates, walking or weight-lifting – which is best for midlife women?

    If you’ve been wondering whether your Reformer Pilates classes are doing enough for your bone strength, Liz has the answer – plus she settles the debate on full-fat versus skimmed milk and explains why it matters for midlife health. In this episode: Is Pilates and walking enough to protect your bones in midlife? Creatine supplements – safe […]

  • Leaky gut, cholesterol and peptides explained – with Dr Mo Enayat

    GP Dr Mo Enayat, founder of HUM2N longevity clinic, joins Liz to reveal the science that could transform how your body ages – and why reaching your 120th birthday might not be as far-fetched as it sounds. In this episode: Leaky gut and zonulin testing for autoimmune conditions Cholesterol explained and why statins might not […]

  • Do I still need HRT if I have no symptoms?

    Should women take HRT even if they’re not bothered by menopause symptoms? It’s a question many women ask – especially those with a family history of osteoporosis. Liz shares her take.  In this episode:  How can I treat bloating and constipation? Are NAD+ and Urolithin A supplements worth taking? What’s the best way to fade a […]

  • A beginner's guide to running in midlife – with Sabrina Pace-Humphreys

    Award-winning runner Sabrina Pace-Humphreys joins Liz to explain why midlife is the perfect time to start running – even if you’ve never run before. They discuss how running became Sabrina’s lifeline through severe postnatal depression, why two runs a week is enough to transform fitness and bone density through menopause, the truth about pelvic floor […]

  • Can I stop my eyesight from getting worse?

    Struggling to read restaurant menus or road signs? If your eyesight seems to be deteriorating faster than you’d like, listen as Liz explores the supplements and lifestyle changes that might actually help protect your vision. Liz is also answering your questions about at-home microneedling tools, perimenopause, creatine and stubborn teenage acne. In this episode: Is […]

  • Collagen banking, tweakments, and the future of skin ageing – with Alice Hart-Davis

    Beauty journalist Alice Hart-Davis joins Liz for an honest guide to non-surgical cosmetic procedures. From biostimulators and polynucleotides to what’s worth the money (and what isn’t), Alice shares 25 years of expertise on what actually works. Resources mentioned:  Learn more about all treatments (and the best practitioners) at The Tweakments Guide NEX peptide skincare One Skin serum […]

  • HRT explained: patches, tablets or gel – and which works best

    From navigating HRT confusion to gut health strategies and the truth about trendy wellness swaps, Liz answers your questions.  In this episode: Mouth taping – can it stop snoring? And does it cause fine lines?  Which type of HRT should I take if I’m exhausted and confused? Collagen supplements and allergies The link between stress […]

  • Food, fasting, and your ageing brain – with Dr Mindy Pelz

    Your brain changes as you age, but Dr Mindy Pelz says that’s not a bad thing. She explains how fasting might be one of the most powerful tools for your ageing brain, which two supplements could make a real difference to both your thinking and your achy joints, why finding purpose matters more than ever […]

  • Protein, fibre and the biohacks women need in midlife – with Rhian Stephenson

    Nutritionist and ARTAH founder Rhian Stephenson joins Liz to explain why biohacking doesn’t need to be extreme – and reveal the simple, powerful fundamentals that actually transform how we feel in midlife. They discuss why most women aren’t hitting their protein targets (and how to frontload your day without relying on powders), and a simple […]

  • How to gently reset health habits in January

    New year, new questions! From gentle New Year resets to supplement timing, Liz tackles your most pressing health questions for the year ahead. In this episode: How to gently reset health habits in January Is the Mirena coil safe with HRT? How to prevent stretch marks during pregnancy How do I rebalance my gut after […]

  • GLP-1s, fibre maxing and light therapy: Liz's take on the trends

    Welcome to the newly revamped Age Better with Liz Earle. To kick off 2026, Liz is playing Love It or Leave It – giving her honest verdict on the wellness trends you’ll be hearing everywhere this year. From chrononutrition and fibre maxing to GLP-1 medications, peptide skincare, and the great oat milk debate, Liz cuts […]

  • image of woman with dark hair named Mary Claire Haver

    Menopause Skin Treatments: Botox, Lasers and Lifestyle

    Nothing needed cutting. The full description comes to 3,601 characters, so it’s under the 4,000 limit: In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Erica Kelly, board-certified dermatologist, Clinical Professor at the University of Texas Medical Branch, and founder and director of UTMB’s Cosmetic Dermatology Division and this time […]

  • 3 Keys for Menopause Fat Loss from a Fat Loss Researcher

    With the endless stream of advice, there are 3 keys for menopause fat loss you need to know. The answer isn’t another diet, harder workouts, or doing even more. One of them might surprise you, because it has nothing to do with giving up when your body composition isn’t changing the way you want. If […]

  • Episode 47: BUSTING THROUGH THE MYSTERIES OF BIPOLAR PERI/MENOPAUSE with JIBZ CAMERON aka DYNASTY HANDBAG

    ⚡️In this week's In this weeks episode Alicia and Jibz Cameron AKA Dynasty Handbag connect the dots between creativity, survival, bipolar disorder and the ways women and AFAB people have been under-treated for decades. We get into her feral childhood origin story and fierce memoir “Hell in a Handbag”, her brilliantly strange alchemy of performance […]

  • The surprising truth about cortisol in midlife – with Dr Erin Kinney

    We often think of cortisol as the big, bad stress hormone we need to keep as low as possible. But what if too little is just as bad for your health? Naturopathic doctor Erin Kinney joins Liz to explain why cortisol is an essential hormone for energy, focus, inflammation and resilience – and why our […]

  • SEEN & HEARD: Breast Cancer at 19: Menopause Symptoms and Life After Diagnosis with Miranda McKeon

    What does it feel like to face breast cancer at 19—and experience menopause symptoms while your friends are in a completely different stage of life? In this episode of Seen & Heard, actress, content creator and women’s health advocate Miranda McKeon shares her experience of being diagnosed with stage 3 hormone-positive breast cancer at just […]

  • How to eat to lower inflammation – the top 5 foods to boost energy, stop pain, and to live longer | Prof Luke O’Neill

    Most of us think of inflammation when an ankle swells or a cut turns red. It’s our body’s immune system, and without it, we couldn’t fight infections or repair injuries.  But when it stays switched on, this chronic inflammation can drain your energy, can affect your health over the years, and even lead to heart […]

  • 237 | What My Pickleball Meltdown Taught Me About Trying to Lose Weight

    What if the biggest thing getting in the way of your ability to lose weight isn’t your food plan—but your mindset? After a VERY competitive pickleball game with my husband, I had one of those moments where I could feel my attitude going downhill…and I let it. Then Romans 8 hit me differently: I don’t […]

  • The Tamsen Show podcast image

    Toe Spacers, Bunions + The Foot Fixes That Could Change How You Age

    If you’ve been searching for how to strengthen your feet, improve your balance, walk better, help bunions, choose the right shoes, or stay mobile as you age, this episode is for you. Your feet could be telling you more about your health than you realize. Today, Tamsen sits down with foot and gait specialist Dr. […]

  • Breast Cancer & Menopause with Gaby Natale, Monica Molenaar, and Dr. Marisa Weiss.

    October is Breast Cancer Awareness Month and in this episode, Stacy is joined by three women who’ve lived where breast cancer and menopause collide: journalist and survivor Gaby Natale, Alloy co-founder/co-CEO and survivor Monica Molenaar, and breast oncologist and survivor Dr. Marisa Weiss of Breastcancer.org. Gaby talks about “breaking the news to yourself” after her […]

  • 104: From Body Bully to Body Ally with Anne Poirier

    Body changes during perimenopause and menopause can bring old struggles with weight, appearance, and self-worth back to the surface. For women who have spent years dieting, restricting food, or trying to change their bodies, learning to relate to a changing body in a different way can be challenging. In this episode, Dr. Jessica Ritch is […]

  • Episode 237 – Beyond Tamoxifen and AIs: Are SERDs the New Kids on the Block?

    What if tamoxifen and aromatase inhibitors weren’t the only options? For many people with hormone receptor-positive breast cancer, endocrine therapy can be lifesaving – but it can also be incredibly difficult to live with. Joint pain, sleep problems, sexual health changes, bone health, weight and metabolic changes can all have a significant impact on day-to-day […]

  • Most replayed moment: The hidden dangers of hearing loss | Prof. Marcelo Rivolta

    The world around us is louder than ever. From booming speakers to roaring traffic, our ears can take quite a beating. But have you ever stopped to consider the long-term impact of all this noise? Because hearing loss isn’t just about your ears. Emerging research suggests it could also affect your brain health in surprising […]

  • 236 | Why Estrogen Changes Where You Store Belly Fat After 40

    Have you looked at your stomach lately and thought, “Wait…where did THAT come from?” Maybe the scale hasn’t changed much, but your waist has. Your jeans fit differently, you’re carrying more belly fat, and the things that worked in your 30s aren’t getting the same response anymore. There’s a reason for that—and in this episode, […]

  • 355 ✨ Giving Up the Ghost: How to Stop Playing Small and Finally Be Seen in Midlife with Samantha Rose, Emmy-Winning Writer & NYT Bestselling Ghostwriter

    What would it take for you to give up YOUR ghost? In this episode of The Midlife Makeover Show, Wendy Valentine sits down with Samantha Rose — Emmy award-winning television writer and New York Times bestselling ghostwriter of nearly twenty books — to talk about what happens when the woman behind everyone else’s stories finally […]

  • image of woman with dark hair named Mary Claire Haver

    Menopause Skin Changes and the Science of Skincare

    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Erica Kelly, board-certified dermatologist, Clinical Professor at the University of Texas Medical Branch, and founder and director of UTMB’s Cosmetic Dermatology Division — and the first physician who ever connected the dots for Mary Claire between estrogen, collagen, and what happens to […]

  • You May Be Mineral Deficient in Menopause: Obvious and Hidden Signs

    This episode is sponsored by BEAM Minerals. BEAM Minerals – Get 20% off your first order at https://beamminerals.com/FLIPPING50 with code FLIPPING50. Could you be mineral deficient in menopause without realizing it? That everyday fatigue, lower energy, or feeling like you’re just not quite yourself may be easy to chalk up to aging or menopause—but what […]

  • 335:The Dignity Gap: Your Dog Gets a Kinder Death Than You Will" : "Death With Dignity – An Honest Talk

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    How to Lower Your Breast Cancer Risk Without Obsessing Over Everything

    Breast cancer is rising in younger women, but why? And what do plastics, alcohol, fragrance, deodorant, PFAS, pesticides, and other everyday exposures actually have to do with breast cancer risk? In this episode of The Tamsen Show, Tamsen Fadal sits down with medical oncologist Dr. Eleonora Teplinsky to separate breast cancer facts from fear and […]

  • How I look after my joints and bones at 63

    Liz discusses the importance of looking after our bone health as we get older and explains the difference between osteoarthritis and osteoporosis. She also shares how she supports her own bone density and joint health, from HRT and strength training to impact exercise, high-protein foods and supplements. Plus: How salt can be used to hydrate, […]

Age Better with Liz Earle

I’m on a mission to change the conversation around ageing. Women’s health – particularly as we age – has been underfunded and overlooked for far too long. And frankly, it’s time we pushed back. Through this podcast, I want to share the knowledge and tools that can help you thrive in later life by taking […]

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