Is alcohol doing more damage in midlife than you realise? – with Prof David Nutt

Age Better with Liz Earle

March 27, 2026 ∙ 60 mins
Episode 28

About

Most of us know alcohol isn’t ideal for our health. But the specific ways it affects the brain, gut, hormones and our sleep, and why those effects become more pronounced as we age, are less well understood.


Leading psychiatrist and neuropsychopharmacologist Prof David Nutt joins Liz to explain exactly what happens in the body from the very first sip, why women become significantly more vulnerable in midlife, and what the science says about how to drink with healthy ageing in mind.


In this episode:

·     Why alcohol affects women’s bodies differently – and more so in midlife

·     What’s actually causing your hangover (it’s not just dehydration)

·     How alcohol damages the gut and suppresses your immune system

·     When even one drink disrupts deep, restorative sleep

·     The brain chemical that makes us want to drink – and how to get it in other ways

·     What drives addiction and why so many people use alcohol to manage stress, anxiety and trauma

·      What cutting back for just one month can do for key health markers

·     The growing world of functional alcohol alternatives


Links mentioned:

·     Liz’s previous podcast with Prof David Nutt

·     Drug Science

·     SENTIA drinks


More from David

·     Follow David on X


Get in touch with a question for Liz:

 

More from Liz:

 

Some links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information.

 

 

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Information

Podcast

Age Better with Liz Earle

Episode

28

Date

March 27, 2026

Length

60 mins
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Age Better with Liz Earle

I’m on a mission to change the conversation around ageing. Women’s health – particularly as we age – has been underfunded and overlooked for far too long. And frankly, it’s time we pushed back. Through this podcast, I want to share the knowledge and tools that can help you thrive in later life by taking […]

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