HRT Gels vs Sprays: What Works Best? Menopause Doctor Naomi Potter

Is It Hot In Here? Midlife Podcast

April 20, 2026 ∙ 14 mins
Episode 25

About

In this week’s episode, Dr Naomi Potter breaks down everything you need to know about HRT gels and sprays — two of the most commonly prescribed forms of transdermal oestrogen. Whether you're interested in trying Lenzetto Spray or Estradiol gel, this episode will be massively helpful for you.


If you’ve ever felt confused about HRT dosing, absorption, or which option to choose, this episode will give you clear, practical answers.


💬 Topics include:


• HRT gels vs sprays: key differences explained

• How to apply oestrogen gel correctly (and common mistakes)

• Why absorption varies between women

• What to do if your HRT isn’t working

• How to safely adjust your dose

• The benefits of transdermal HRT (lower clot risk)

• How long you can stay on HRT

• Practical tips to fit HRT into your daily routine


Follow Is It Hot In Here? podcast on Instagram at @podcast_naomipotter


Follow Dr Naomi Potter below:

Naomi’s Instagram: @dr_naomipotter

Naomi’s TikTok: @dr_naomipotter


More info and menopause support at: https://www.menopausecare.co.uk/


00:00 – Intro: HRT Gels vs Sprays Explained

00:35 – HRT Gel: How It Works & How To Use It

02:43 – Where & When To Apply Gel (Key Tips)

05:52 – Why Choose Gel? (Pros & Practicalities)

06:39 – HRT Spray (Lenzetto): What It Is & How It Works

07:32 – Spray vs Gel: Dosing & Key Differences

08:49 – Spray Pros & Cons (Absorption & Ease)

10:01 – When To Replace Your Spray (Important!)

10:46 – How Long Can You Stay On HRT?

11:32 – Switching Between Gel & Spray

12:35 – Why Transdermal HRT Is Safer


#hrt #menopause #perimenopause

Information

Podcast

Is It Hot In Here? Midlife Podcast

Episode

25

Date

April 20, 2026

Length

14 mins
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Is It Hot In Here? Midlife Podcast

Part open-clinic, part talk show, this is the podcast for women navigating perimenopause, menopause, and midlife health. Each week, menopause Doctor Naomi Potter is joined by a new guest to explore the real-life impact of their hormonal changes. From hot flushes and anxiety, to brain fog and sleep problems, no topic is off limits. Whether […]

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