How to Slow Aging and Feel Younger Fast with Epigenetics

The Flipping 50 Show

February 25, 2025 ∙ 40 mins
Episode 71

About

Slow aging is no longer a mystery — it’s rooted in the science of epigenetics. This includes lifestyle, diet, and environment influence your biological age. Understanding biological versus chronological age reveals strategies to live longer and feel younger.

Today’s episode covers tools and insights for changing biological age. If you're ready to slow aging and feel younger fast, this episode is for you.

My Guest:

Hannah Went, a Biology graduate from the University of Kentucky, is passionate about longevity and breakthrough technologies. After researching cell signaling and biology, she saw the potential of methylation-based diagnostics.

She founded TruDiagnostics to focus on life extension and preventive healthcare, serving functional medicine providers. TruDiagnostic has over 30 clinical trials and one of the largest private epigenetic health databases. Hannah also created Everything Epigenetics to share insights on DNA regulation’s impact on health.

Questions We Answer in This Episode:

  • How has the concept of “real age” or biological age evolved from simple quizzes to blood-based testing? 00:05:15
  • What is epigenetics? 00:08:35
  • What is the difference between epigenetics and genetics? 00:10:45
  • What is biological age? 00:15:15
  • How can biological age be measured and how accurate is it? 00:19:15
  • How quickly can we change biological age? 00:20:55
  • What mistakes do women commonly make when investing time, money, and energy to slow aging? 00:27:15
  • Can you share any stories of dramatic changes in biological age? 00:30:25

Connect with Hannah:

https://www.flippingfifty.com/epigenetics

On Social:

Instagram: https://www.instagram.com/everythingepigenetics/

Twitter: https://twitter.com/EverythingEpi

Other Episodes You Might Like:

Ageless Aging: Believe it or Not?: https://www.flippingfifty.com/ageless-aging/

How To Defy Aging Naturally without Needles or Knives: https://www.flippingfifty.com/defy-aging-naturally/

Resources:

VIP Private Coaching: https://www.flippingfifty.com/store/coaching-programs/90-day-private-coaching-5000

Discovery Call with Debra: https://www.flippingfifty.com/wellness-coaching-for-life/

Information

Podcast

The Flipping 50 Show

Episode

71

Date

February 25, 2025

Length

40 mins
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    If you or someone in your family deals with Parkinson’s, Alzheimer’s or you’re simply in midlife dealing with changing hormones, this episode and the book we’re discussing, Heal your gut, save your brain, will be one you don’t want to miss. My Guest: Dr. Partha Nandi, M.D., F.A.C.P is the creator and host of the […]

  • I Asked Chat Gpt for 3 Menopause Strength Workouts – Here’s What I Got

    Here are three strength training workouts designed specifically for women in menopause. These focus on maintaining muscle mass, boosting bone density, and supporting hormone balance. Each workout should be done 2–3 times a week, allowing at least one rest day between sessions. Workout 1: Full Body Strength (45 min) Warm-up (5-7 minutes): March in place […]

  • Better Sex In Menopause and Beyond

    How’s better sex in menopause sound? For many it sounds like a distant and foreign trip. Sex is one of the most popular topics on the show. Many women tell me their partners are glad they’re attending. Sex is such a hot topic (see what I did there?) that low libido was a topic answered […]

  • Caregiver to Midlife Crisis to Over 50 Fitness Athlete

    The Doctor is in the house and she’s an over 50 fitness athlete. She’s juggled all the balls you may have from a caregiver and midlife crisis like me. But she’s returned to her prior passion for fitness competitions. Or has she? I’ll ask that question – is it the competition or the training or […]

  • An Intermittent Fasting Update with Cynthia Thurlow

    In this episode with returning guest and fan fave, Cynthia Thurlow we discuss updates on intermittent fasting. If you’re craving a behind the scenes, more than science-geek relay of the power of autophagy episode you shall have it. I’m looking forward to sharing this one with you. My Guest: Cynthia Thurlow is a globally recognized […]

  • Optimizing Hormones Early in Perimenopause

    My Guest: Emily Sadri is a Board Certified Women’s Health Nurse Practitioner, Certified Nurse Midwife, and the founder of Aurelia Health, a modern telemedicine practice for women over 35. Aurelia Health provides comprehensive hormone replacement therapy and weight loss support with long visits and un-rushed care. Emily is passionate about making complex hormonal topics accessible […]

  • How I Choose Podcast Guests and Controversial Topics

    In this episode, it’s all about how I choose podcast guests. First before we get started, I appreciate your thoughts. I work hard on keeping an open mind and listening to suggestions. Though I can’t take action on all of them, we are here because of you. There’s this dance between the expert, experienced, the […]

  • Why Am I Sore in Menopause and What to Do About It

    In this episode you’ll hear me respond to one of our Flipping 50 members asking a question about being sore in menopause, for no reason. If you’re sore, stiff, or even have a little niggle or “catch,” this is for you. If you’ve passed this kind of thing off for arthritis or getting old, stick […]

  • Six Powerful Ways To Keep Your Perimenopause Brain Sharp

    Whether you or your daughter, or someone you know, the perimenopause brain can be a “thing. If you’ve been tuning in to Flipping 50 long enough, you’re familiar with symptoms of menopause. In this episode, I explore the connections of symptoms to brain health. With my guest, we’ll share how bHRT or Bioidentical Hormone Replacement […]

  • Timetable for Strength Training Benefits in Menopause

    You’re just a workout, even a warm up set, away from strength training benefits in menopause. In this episode you will learn or get a refresher on just how soon you can expect to get those immediate results we all crave. Unlike Amazon you can’t get them dropped on your doorstep in a few hours, […]

  • From Managing Menopause to Winning Menopause What’s Your Story?

    Just to be clear, this podcast is less about managing menopause in the physical sense of the term and more about what you might be telling yourself about it. If you are stuck in the messy middle, or you’re itching for a change, and perhaps just don’t know what that is, this is for you. […]

  • 2 Big Obstacles to Gaining Lean Muscle and Fat Loss After 40

    Chances are if you tuned into this based on the title you’re not exactly where you want to be right now. Fat loss after 40 could be a challenge in spite of your best effort. Gaining lean muscle could feel like it’s slipping through your fingers. To those regular listeners who are here no matter […]

  • What is Glutathione and How Can it Support Menopause?

    What is Glutathione and How Can it Support Menopause? What is glutathione? Not to be confused with glutamine, it may be something you are less aware of and it certainly doesn’t make it into conversations where creatine and amino acids are. So is glutathione one of the cool kids you need to hang out with? […]

  • Training for Adventure Retreats Heat, Altitude, Oh My

    Training for adventure retreats, aka, bucket list experiences is so much more motivating and fun than routing strength training for bone density or lose belly fat. Some might focus on fitness goals, while others are drawn to living life to the fullest through challenging adventures. So who are you? You don’t have to pick a […]

  • The Real Reason for Migraines and Constipation in Menopause

    The Real Reason for Migraines and Constipation in Menopause Do you experience migraines and constipation in menopause? Did they begin with more frequency during perimenopause? Why does this happen? Are these common or is it just me? Migraine and constipation can be symptoms of perimenopause and menopause. These may get in the way of our […]

  • Things I Wish More Women Over 40 Knew About Exercise

    Things I Wish More Women Over 40 Knew About Exercise This is what I wish more women over 40 knew about exercise and that it starts when women are teenagers. So, I’ll start there. I’ve worked with women for 40 years in private sessions, partner sessions, group sessions, with both husbands and wives, and with […]

  • The Book Busting Menopause Myths That Women (and Their Doctors) Believe

    Busting Menopause Myths Estrogen causes breast cancer, gaining weight and belly fat which are inevitable… Today we are busting menopause myths just like this. In this episode, I interview a pair of authors offering refreshing insight to midlife and beyond women who are often sheltered from all the health options available to them and misinformed, […]

  • Fit or Fat? Training and Measuring Fitness in Menopause

    Measuring fitness in menopause is complicated. I’m going to take a stab at this and let you know that if you’re not measuring beyond your weight, body composition, inches, and muscle mass at regularly scheduled intervals, you’re doing a disservice. We get all up in the business of burning calories (wrong goal), having it “feel […]

  • Running Long in Midlife and Beyond One 50-mile Run for a 50th Birthday

    50 miles for 50th bday? Running long in midlife isn’t the first thing (or second) I recommend to women. But what happens when your peak estrogen levels were at least a decade ago? What if you’ve got a crazy goal, want to go for it, and you know how to interpret reactions and respond accordingly? […]

  • 5 Non-Exercise Ways to Boost Fat Burn

    This simple list of non-exercise ways to boost fat burn has turned my YouTube channel subscribers upside down! Meaning they’ve flipped over them! It’s crazy! Secretly my hope is that YOU are using these as extra insurance, and not your only line of defense. Increase Water Intake to Boost Hydration Increase Protein Intake Thermogenic effect […]

  • Natural Solutions to Restorative Sleep in Menopause

    Natural Solutions to Restorative Sleep in Menopause Restorative sleep in menopause can be elusive, I think we can all agree on that! Whether perimenopause or post, fluctuating hormones combined with chaos that midlife can be, can kiss sweet dreams goodbye. But it’s the exact opposite of what you need to most easily make weight loss […]

  • Research About Menopause: What's Real and What’s Marketing?

    Research about menopause right now is finally beginning to really get its moment. Or is it? What’s something you can trust? And what’s stated as “science-based” or “science-backed”? What can you trust and what should you question? Think of this as a crash course in Research 101. In fact, I think that was a required […]

  • How To Defy Aging Naturally without Needles or Knives

    Do you want to defy aging naturally and not with botox or fillers? This is a no-judgment zone. I am guessing that if you have opted for Botox or filler, you think twice about it. Wondering about somewhere more fun to spend that $500 with no toxic effect or superficial fake and dead-giveaway that a […]

  • Can You Wear a Weighted Vest with Osteoporosis?

    The short answer is yes. The long answer here in this episode is how. Using a weighted vest with osteoporosis comes up frequently as a question. Whether or not you have osteoporosis, stay with me, as I will talk about the overall benefits and science that’s been out since at least 2000, perhaps as long […]

  • TRAVELING ALONE AFTER 50 OR WITH FRIENDS? Safe vs Not Safe

    Dreaming of traveling but your friends aren’t? How can we step up our game and really get the adventure and bucketlist life we want? I challenge you… and me to take the trip we want. Traveling alone is not just a destination trip, it’s very possibly a destination to yourself. How liberating would that be. […]

  • Truths and Myths: Lifting Heavy in Menopause for Bones & Body Comp

    Have you ever wondered if it’s possible to begin lifting heavy weights during midlife, perimenopause, or menopause? Let’s talk about how lifting can be very beneficial to your bones, connective tissues, and everyday life. For beginners, you have to start slowly and surely, lifting until we feel that sweet spot. And for those lifting for […]

  • Detoxifying Your Body from the Damage of Diets in Menopause

    The damage of diets, and often in midlife, a lifetime of it can be the limiting factor in your weight loss, your fitness, and your longevity. Girls start dieting as early as 13, sometimes even younger, leading to lifelong struggles with self-image. We talk with a male trainer specializing in helping women in their 50s […]

  • 23 Lab Tests in Menopause and What They Tell You

    In this episode I’m sharing my recent lab test, 23 lab tests in menopause, to be exact. I’ll share why so many, how often, what I’ll learn from them. If you’re at a loss for what to order or really, what you need and want a doctor to run this will help. Connecting the dots […]

  • Why Insulin Resistance in Menopause is So Important

    How do you know you’re experiencing insulin resistance in menopause? How would you know that weight gain or belly fat may be a result of your insulin resistance? My guest today has type 1 diabetes and shares today the nuances of how to deal with midlife hormonal changes at the same time as dealing with […]

  • 5 Ways to Improve Your Mitochondria

    Improve Your Mitochondria To improve your mitochondria requires you focus a little more than on just “exercise” or “anything is better than nothing.” First, though, let’s talk about why you want to. Now, if you want a deeper conversation, I’ve got a couple resources for you. There are prior Flipping 50 episodes I’ll link to […]

  • 78 Year Old Endurance Athlete Training for Triathlons

    Rarely do we look at training for endurance or being an endurance athlete here. Today is different. This isn’t a suggestion nor a recommendation. But it is a glass ceiling lift. Whatever you think is possible, is possible. There are few 78-year-olds training for 4-5 hours on a bike or spending hours a week in […]

  • One Thing I Would Change After 40 Years Working with Women in Menopause

    One Thing I Would Change After 40 Years Working with Women in Menopause Working with women in menopause for 40 years, even before it dawned on me that’s what I was doing, I know now what I wish I’d have done differently. I’ve never said this out loud quite like this, though I’ve hinted at […]

  • Lose Weight in Menopause Faster and Easier Than You Ever Thought Possible

    If you have repressed metabolic syndrome your quest to lose weight in menopause faster and easier is sunk. But stay tuned to this episode. In this Flipping 50 episode with podcast guest favorite, Stu Schaffer we talk about the #1 goal most of you tell me is yours… weight loss. More specifically weight loss in […]

  • Protein Consumption in Menopause

    When it comes to protein consumption in menopause, there are several things to consider. Even though there’s no science or medical evidence to show higher (than you grew up with or are used to) protein intakes cause kidney (renal) issues, many people still believe it’s true. What is true is or anyone who has an […]

  • How to Eat Out Without Blowing It!

    Registered dietitian Bonni London joins me today to talk about how to eat out without blowing it and how to decide if fasting is something you want and need and if so how. Let’s talk about your definition of healthy. Is it for weight loss, weight maintenance, or is it to reverse an illness? Stay […]

  • Progressive Relaxation in Menopause: A Unique Practical Podcast Episode

    I love progressive relaxation in menopause as a tool to do just that. Whether it’s to take a 10 minute break or get to sleep or back to sleep, it works. This method is a powerful tool to reduce stress, improve sleep, and enhance overall well-being. Incorporating this practice into your routine can make a […]

  • Too Much or Not Enough Variety in Exercise in Menopause?

    The Importance of Basics and Variety in Exercise in Menopause Exercise during menopause can be challenging, but focusing on basics is key. These exercises build and maintain lean muscle mass and bone density, which are crucial as women age. For women over 40, sticking to basics provides significant benefits. Incorporate new exercises into warm-ups and […]

  • Symptoms of Breast Cancer (YouTube Video #389)

    Symptoms of Breast Cancer In this eye-opening episode, Dr. Barbara 'Menopause' Taylor reveals a surprising truth—most breast cancers have no early symptoms. She debunks common myths, especially the widespread belief that breast pain signals cancer, and explains the difference between signs and symptoms. Learn why relying on symptoms alone can be dangerous, and how early […]

  • Sherri Dindal – Being The Real Slim Sherri and new beginnings in Midlife & Menopause

    Many of you will know The Real Slim Sherri from Instagram and TikTok – she is well known for her no- holds barred, unfiltered truths around growing up in the 70’s and 80’s, midlife, life as a Gen X woman and menopause.  I have loved her page ever since I discovered it and so was […]

  • What Stem Cell Therapy Taught Me About Recovery, Mindset, and Reinventing Downtime

    In today’s episode, I share my personal experience with stem cell therapy—and the unexpected lessons that came from being forced to slow down. Whether you’re choosing a procedure like stem cell therapy or suddenly dealing with an injury or illness, time off from your normal routine isn’t just inconvenient — it’s a major mental and […]

  • 193 Can Color Heal You? Dr. Deanna Minich Thinks So 🎨🧠🌿

    Forget everything you thought you knew about nutrition. This episode gets wildly colorful—literally. Dr. Deanna Minich joins Sally to decode how COLOR—yes, actual colors—can shift your health, your hormones, and even your mood. From purple carrots to chlorophyll, this convo goes deep on how to nourish your body and your energy. We’re talking:✨ Yellow for […]

  • Ep #152: Overcoming Gender Barriers in a Male-Dominated Industry with Captain Reyné O’Shaughnessy

    In this episode, Andrea Donsky, nutritionist, published menopause researcher, menopause educator, and co-founder of WeAreMorphus.com, talks to Captain Reyné O’Shaughnessy. She is a veteran commercial airline pilot with over 34 years at a Fortune 50 carrier and more than 10,000 heavy-jet flight hours, including being among the first women qualified on the Boeing 747. She's […]

  • 219 How to Support Your Mental Health and Stop Menopause Weight Gain

    Menopause is a natural part of life, but that doesn’t mean it’s easy. I’ve experienced the exhaustion, the thinning hair, the mood swings—and the confusion that comes when you feel like your body is changing faster than you can keep up. In this episode, I’m sharing my personal journey with menopause and the lessons I’ve […]

  • S4 Ep178: Mid-life Nutrition: Tips and Tricks From a Dietician with Dr. Alexandra Filingeri

    Any mid-life woman knows that once you hit your 40s, 50s, or 60s, things will not go well if you eat the same way you did when you were 20. But it’s confusing to know what to eat, and how much to eat, without downloading multiple APPs and carrying around a calculator  My guest, Alexandra […]

  • 164: Emotional Eating in Menopause – The Psychology Behind the Cravings

    Do you get cravings for the foods that make your soul feel fuzzy but your body feel icky? In this episode, Adele explains the psychology behind those cravings, how to make steps away from those cravings and how to be more mindful with your eating. Check out Adele’s FREE symptom assessment here: https://adelejohnstoncoaching.com/free-copy-of-our-symptom-assessment/ Adele is […]

  • Thursday Thoughts – Writing a Book

    This week on Thursday Thoughts, Lucy and I dive into a juicy conversation all about her brand new book Shiny Happy Singles — or Thrive Solo if you're tuning in from the US. We chat about the inspiration behind the book, what it really means to thrive on your own, and why this message is […]

  • From Midlife Crisis to Midlife Chrysalis: Chip Conley’s Roadmap to Reinvention

    In this episode of Hello Menopause, Stacy talks with entrepreneur, author, and Modern Elder Academy founder Chip Conley about what it really means to navigate midlife. Drawing from his own experience with prostate cancer and hormone therapy, Chip shares what it felt like to go through “male menopause” and how that informed his vision for […]

  • Bladder Issues in Menopause – The Hidden Bacteria You Need to Know

    If bladder issues in menopause are keeping you from jumping for bone density or for jumping for joy. Or if laughing and sneezing or a need to consider hydration needs against access to a bathroom are real life and every day concerns you… we’ve got you today.  Bladder issues in menopause don’t need to keep […]

  • Ep 176 -Restoring Blood Flow for Brain, Heart and Hormonal Health with Cathy Eason

    In this week’s episode,  Dr. Fiona Lovely speaks with Cathy Eason, a certified holistic nutritionist and clinical educator, about nitric oxide (NO), often called the “miracle molecule” for its vital role in blood flow and thus, overall health.  We talk about the groundbreaking findings from a pilot study on nitric oxide’s impact on women’s sexual […]

  • Ep 481: The 5,000-Year-Old Secret to Stopping Emotional Eating

    I’m showing you how ancient Buddhist wisdom can help you break the cycle of emotional eating with more awareness, compassion, and ease—just like I teach my clients. Get the full show notes and information here: https://drdebbutler.com/481

  • #129: 7 Essential Habits to Move Through Menopause with More Ease

    Midlife doesn’t have to be a crisis — it can be a genuine metamorphosis. In this episode, I’m not talking about just surviving menopause.I’m talking about moving through it with more ease, clarity, and actual calm. You’ll hear a segment from a training I recently ran, where I shared seven essential habits that helped me […]

  • 13 – HRT after 60: myths, facts and finding your own path with Ann Newson

    In this week’s episode, Dr Louise Newson is joined by her mother, Ann Newson, for a candid and deeply insightful conversation about HRT after 60, as requested by some ofour viewers.  Together, Dr Louise and Ann address the persistent fears around breast cancer and HRT, revisiting data from the controversial 2002 WHI study. They also explore the […]

The Flipping 50 Show

The podcast for women in menopause and beyond who want to change the way they age. Fitness, wellness, and health research put into practical tips you can use today. You still got it, girl!

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